Name: PE 22-28
CAS Registry number: 1801959-12-5
Molecular Formula: C??H??N??O?
Molecular Weight: 773.89 Da
Purity: ≥99% (by HPLC)
Appearance: White lyophilized powder
Packing: 10 vials/box
Brand: Shengshizhiyang
Storage Conditions: Store at -20℃ in a dry, dark place; avoid repeated freeze-thaw cycles.

Brief Introduction:
PE 22-28 is a synthetic peptide derived from Spadin, acting as a selective inhibitor of the TREK-1 potassium channel. It is designed for research use only, particularly in the fields of neuroscience, depression mechanisms, and neuroprotection studies.

Main Research Applications:
1. Depression and mood disorder research: Used in preclinical models to investigate TREK-1 channel inhibition and its effects on mood regulation and antidepressant-like activity.
2. Neuroprotection and ion channel studies: Applied in research on potassium channel function, neuronal excitability, and neuroprotective mechanisms.
3. Pharmacological mechanism research: Suitable for exploring the role of TREK-1 channels in central nervous system signaling and related therapeutic targets.

Note:
This product is for laboratory research use only. It is not intended for human or animal therapeutic use, clinical trials, or any form of in vivo administration without prior ethical approval and regulatory authorization.