Name: PNC 27
CAS Registry number: 1159861-00-3
Molecular Formula: C???H???N??O??S
Molecular Weight: 4031.7 Da
Purity: ≥99% (by HPLC)
Appearance: White lyophilized powder
Packing: 10 vials/box
Product Group: Peptide
Storage Conditions: Store at -20℃ in a dry, dark place; avoid repeated freeze-thaw cycles.

Brief Introduction:
PNC 27 is a synthetic chimeric peptide combining the HDM-2-binding domain of p53 with a membrane-penetrating sequence. It is designed for research use only, particularly in oncology and cancer cell biology studies.

Main Research Applications:
1. Anticancer mechanism research: Used in preclinical models to investigate selective cancer cell lysis via HDM-2 binding and transmembrane pore formation.
2. Oncology and tumor biology studies: Applied in research on acute myeloid leukemia, cancer cell necrosis, and targeted peptide interactions with cancer cell membranes.
3. Molecular and cell biology research: Suitable for exploring peptide-membrane interactions, HDM-2 signaling pathways, and selective cancer cell targeting mechanisms.

Note:
This product is for laboratory research use only. It is not intended for human or animal therapeutic use, clinical trials, or any form of in vivo administration without prior ethical approval and regulatory authorization.