Cagrilintide – High Purity Premium Lipidated Peptide API

Product Overview Cagrilintide is a long-acting lipidated synthetic amylin analogue and dual agonist targeting amylin receptors (AMYRs) and calcitonin receptors (CTR). Modified via fatty acid acylation, it binds reversibly to serum albumin, greatly prolonging in vivo half-life to support once-weekly administration, and avoids amyloid fibril aggregation of native amylin. It slows gastric emptying, suppresses postprandial glucagon secretion, activates central satiety signaling pathways in the brainstem and hypothalamus, lowers hepatic glucose output, and jointly regulates glucose homeostasis and energy balance. Different from GLP?1 agonists, it acts through an independent receptor pathway and generates synergistic weight-lowering and glycemia-controlling effects when combined with semaglutide.

It is applied in laboratory research including obesity mechanism study, type 2 diabetes glycemic regulation, satiety signal pathway exploration, gastric emptying pharmacology, combined metabolic drug efficacy verification and amylin receptor pharmacological evaluation. It is extensively adopted in metabolic signal cascade analysis, energy balance regulation tests and long-acting peptide pharmacokinetic research.

Adopting optimized solid-phase peptide synthesis, cysteine disulfide bond cyclization and lipidation modification purification technology, the product shows excellent solubility in aqueous buffer and stable biological activity after reconstitution with designated solvent. CAS Number: 1415456-99-3

Technical Specifications & Quality Standards

HPLC Purity: ≥99.0% Identity Test: HPLC verification + full mass spectrometry peptide sequencing + disulfide bond mapping, molecular weight fully matches theoretical standard value Appearance: Aseptic lyophilized white fine powder

Strict CQA Quality Control: Full-item detection including residual organic solvents, heavy metal content, bacterial endotoxin, microbiological limits, lipidation modification rate and disulfide bond conformation verification;

The entire production line follows standardized GMP management system, guaranteeing uniform quality among different batches.

Supply & Order Instructions

Production Capacity: Stable large-scale manufacturing available, supporting kilogram-level bulk procurement and small-volume trial sample orders

Lead Time: Bulk kilogram orders need one month advance reservation owing to complex cyclization and lipidation synthesis routes plus multi-round strict impurity inspection processes; sample orders enjoy shorter delivery cycle.

Quality Assurance

Each shipment batch is attached with a full official Certificate of Analysis (COA). The product maintains purity over 99.0% with intact biological activity; third-party independent laboratory re-inspection is acceptable for authenticity confirmation.

Payment Options

Alibaba Trade Assurance, PayPal, USDT, Bank Wire Transfer, Western Union

Core Advantages

Standard regular packaging: inner glass vial + outer carton, suitable for long-term low-temperature sealed storage away from light In-house professional peptide R&D laboratory team, providing customized specification repackaging and concentration dilution service

Confidential worldwide delivery equipped with dedicated low-temperature cold-chain packaging to prevent peptide structural degradation and lipid group shedding during long-distance transportation