ARA-290 (Cibinetide) – High Purity Premium Peptide API

Product Overview ARA-290, also named Cibinetide, is an 11-amino-acid synthetic peptide derived from the helix B domain of erythropoietin (EPO). It selectively targets the innate repair receptor (IRR), a heterodimer complex formed by EPOR and CD131 (β common receptor), and does not bind to the classical EPOR homodimer responsible for erythropoiesis. It completely abandons the erythrocyte-stimulating activity of EPO while retaining full-spectrum tissue protection, anti-inflammation, anti-apoptosis and nerve regeneration functions. It can suppress pro-inflammatory factors such as TNF-α and IL-6, alleviate ischemia-reperfusion injury, accelerate wound repair, restore damaged small nerve fibers, improve insulin resistance and stabilize metabolic homeostasis, with low systemic adverse reactions and high tissue targeting safety.

It is applied in laboratory research including peripheral neuropathy mechanism, neuroinflammation regulation, ischemic organ protection, diabetic complication intervention, wound angiogenesis remodeling and innate repair receptor pharmacology verification. It is extensively adopted in injury repair signaling pathway exploration, neuroprotective pharmacodynamic testing and selective peptide receptor research experiments.

Adopting optimized solid-phase peptide synthesis and cyclization purification technology, the product features excellent water solubility and stable spatial conformation; biological activity remains intact after reconstitution with designated solvent. CAS Number: 1208243-50-8

Technical Specifications & Quality Standards

HPLC Purity: ≥99.0% Identity Test: HPLC verification + full mass spectrometry peptide sequencing + N-terminal pyroglutamate cyclization conformation identification, molecular weight fully matches theoretical standard value Appearance: Aseptic lyophilized white fine powder

Strict CQA Quality Control: Full-item detection including residual organic solvents, heavy metal content, bacterial endotoxin, microbiological limits, cyclization rate and peptide sequence consistency inspection;

The entire production line follows standardized GMP management system, guaranteeing uniform quality among different batches.

Supply & Order Instructions

Production Capacity: Stable large-scale manufacturing available, supporting kilogram-level bulk procurement and small-volume trial sample orders

Lead Time: Bulk kilogram orders need one month advance reservation owing to cyclization modification routes and multi-round strict impurity detection processes; sample orders enjoy shorter delivery cycle.

Quality Assurance

Each shipment batch is attached with a full official Certificate of Analysis (COA). The product maintains purity over 99.0% with intact biological activity; third-party independent laboratory re-inspection is acceptable for authenticity confirmation.

Payment Options

Alibaba Trade Assurance, PayPal, USDT, Bank Wire Transfer, Western Union

Core Advantages

Standard regular packaging: inner glass vial + outer carton, suitable for long-term sealed storage at -20℃ protected from light In-house professional peptide R&D laboratory team, providing customized specification repackaging and concentration dilution service

Confidential worldwide delivery equipped with low-temperature cold-chain packaging to prevent peptide conformational degradation during long-distance transportation