Name: MT-1

Alias: Melanotan 1, Afamelanotide CAS Registry number: 75921-69-6 Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH? Molecular Formula: C??H???N??O?? Molecular Weight: 1646.85 Da Purity: ≥99% (by HPLC) Appearance: White lyophilized powder Packing: 10 vials/box Product Group: Peptide

Storage Conditions: Store at -20℃ in a dry, dark place; avoid repeated freeze-thaw cycles.

Brief Introduction:

MT-1 (Melanotan 1 / Afamelanotide) is a synthetic 13-amino-acid tridecapeptide analog of α-MSH for laboratory research only. It exhibits high selectivity for MC1R melanocortin receptors on melanocytes, directly triggering eumelanin synthesis without UV irradiation. It is widely used in dermatology, photobiology and pigmentation mechanism research for its photoprotective and skin pigment regulating properties.

1. Melanogenesis & pigmentation research: Applied in melanocyte cell models to explore MC1R signal cascade, eumelanin production and dose-dependent skin pigmentation changes.
2. Skin photoprotection research: Used to study UV-induced DNA damage relief, antioxidant defense and light-sensitive skin disease intervention mechanisms.
3. Dermatological disorder research: Suitable for experimental study of hypopigmentation disorders, erythema and photosensitivity-related lesions.
4. Melanocortin receptor selectivity research: For comparative analysis of MC1R-specific agonist characteristics versus non-selective melanocortin peptides like MT-2.Note: