Alias: Bremelanotide CAS Registry number: 1607799-13-2 Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys (cyclic lactam bridge between Asp and Lys)
Molecular Weight: 1025.16 Da Purity: ≥99% (by HPLC) Appearance: White lyophilized powder Packing: 10 vials/box Product Group: Peptide

Storage Conditions: Store at -20℃ in a dry, dark place; avoid repeated freeze-thaw cycles.

Brief Introduction:

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analogue of α-MSH for laboratory research only. It selectively activates central MC3R and MC4R melanocortin receptors, with weaker pigmentation effect compared with MT-2. It regulates sexual arousal and desire through central nervous system pathways, independent of peripheral vascular relaxation mechanisms. Widely used in neuroendocrine, sexual behavior and melanocortin signaling research.

1. Neuroendocrine sexual function research: Applied in animal models to study central pathways regulating sexual desire, arousal and sexual dysfunction mechanisms in both male and female subjects.
2. Melanocortin receptor signaling research: Suitable for comparative analysis of MC3R/MC4R signal transduction, contrasted with broad-spectrum agonist MT-2.
3. Appetite & energy metabolism research: Used to explore central satiety regulation and MC4R-mediated energy balance physiological processes.
4. Central nervous system neuroinflammation research: For preliminary study of melanocortin peptide-mediated brain anti-inflammatory pathways.

Note:

This product is for laboratory research use only. It is not intended for human or animal therapeutic use, clinical trials, or any form of in vivo administration without prior ethical approval and regulatory authorization.