Name: AICAR

Alias: Acadesine, AICA Riboside, 5-Aminoimidazole-4-carboxamide ribonucleoside CAS Registry number: 2627-69-2 Molecular Formula: C?H??N?O? Molecular Weight: 258.23 Da Purity: ≥99% (by HPLC) Appearance: White crystalline powder Packing: 10 vials/box (50mg per vial) Product Group: Nucleoside Research Compound

Storage Conditions: Store at -20℃ in a dry, dark place; avoid repeated freeze-thaw cycles.

Brief Introduction:

AICAR (Acadesine) is a cell-permeable adenosine analog nucleoside compound solely for laboratory research use. After entering cells, it is phosphorylated to ZMP to mimic AMP and activate AMPK, the core energy-sensing protein kinase. It simulates exercise-induced metabolic changes without physical activity, widely studied for glucose homeostasis, lipid oxidation, endurance regulation, cardiovascular protection and anti-inflammatory mechanisms.

1. Energy metabolism & endurance research: Used in cell and animal models to explore AMPK-mediated fat oxidation, slow-twitch muscle fiber transformation and exercise endurance improvement pathways.
2. Type 2 diabetes & glycemic regulation research: Applied to study insulin-independent glucose uptake, hepatic gluconeogenesis suppression and insulin resistance alleviation mechanisms.
3. Cardiovascular ischemia protection research: Suitable for investigating myocardial anti-oxidation, reperfusion injury relief and endothelial function maintenance.
4. Metabolic & tumor signaling research: For exploring AMPK-related autophagy, adipocyte differentiation inhibition and tumor cell proliferation regulation.

Note:

This product is for laboratory research use only. It is not intended for human or animal therapeutic use, clinical trials, or any form of in vivo administration without prior ethical approval and regulatory authorization.