Name: Mazdutide

Alias: IBI-362, OXM-3 CAS Registry number: 2259884-03-0 Sequence: His-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Glu-Lys-Lys-Ala-Lys(AEEA-AEEA-γGlu-Nonadecanoic acid)-Glu-Phe-Val-Glu-Trp-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-NH? Molecular Formula: C???H???N??O?? Molecular Weight: 4563.06 Da Purity: ≥99% (by HPLC) Appearance: White lyophilized powder Packing: 10 vials/box (10mg total per vial) Product Group: GLP-1R/GCGR dual agonist metabolic peptide

Storage Conditions: Store at -20℃ in a dry, dark place; avoid repeated freeze-thaw cycles.

Brief Introduction:

Mazdutide is a lipidated long-acting oxyntomodulin analog exclusively for laboratory research. It dual activates GLP-1 and glucagon receptors. GLP-1 signaling slows gastric emptying, suppresses appetite and boosts glucose-dependent insulin secretion. GCGR activation elevates energy expenditure and accelerates hepatic lipolysis. It lowers body weight, stabilizes blood glucose and reduces liver fat accumulation, widely applied in obesity, type 2 diabetes, hepatic lipid metabolism and cardiometabolic research.

Main Research Applications:

Appetite & glycemic research: Used in cell and animal models to study satiety control and postprandial glucose regulation pathways. Adipose metabolism research: Suitable for exploring fat breakdown, energy consumption and visceral weight loss mechanisms. Hepatic lipid research: Applied to investigate liver fat reduction and non-alcoholic fatty liver intervention effects. Cardiometabolic research: For comparative analysis of blood lipid, blood pressure and uric acid improvement.

Dual receptor pharmacology research: Study synergistic metabolic effects of GLP-1/GCGR co-activation.